With even more benefits, this curcumin spice also has anti-inflammatory properties, significantly inhibiting the production of the pro-inflammatory cytokine, interleukin-18 (an inflammatory protein), thus is helpful for preventing joint inflammation and has been shown to be an effective nutritional supplement for arthritis and osteoarthritis. Further, curcumin has been found to be potentially cytotoxic to tumor cells, suppressing the growth of numerous cancer cells, including those of the prostate, biliary, pituitary gland, oral, and uterine leiomyoma. Curcumin has also displayed antimicrobial and anti-fungal properties, specifically against Candida strains. As well, curcumin could be an effective adjuvant therapy for individuals with type II diabetes, due to its possible anti-hyperglycemic effect and results showing improved insulin sensitivity. Additionally, curcumin supplementation has demonstrated evidence for maintaining circulatory health by showing a reduction of lipids in patients with acute coronary syndrome.